Bugs in the system

Bugs in the system

Source :

• Immunological Reviews [ 0105-2896 ] ; 2013-09.

Descripteurs français

• KwdFr :
  • Animaux, Biologie des systèmes (tendances), Humains, Interactions hôte-pathogène, Phénomènes physiologiques viraux, Recherche médicale translationnelle, Virologie (tendances).
• MESH :
  • tendances : Biologie des systèmes, Virologie.
  • Animaux, Humains, Interactions hôte-pathogène, Phénomènes physiologiques viraux, Recherche médicale translationnelle.

English descriptors

• KwdEn :
  • Animals, Host-Pathogen Interactions, Humans, Systems Biology (trends), Translational Medical Research, Virology (trends), Virus Physiological Phenomena.
• MESH :
  • trends : Systems Biology, Virology.
• Teeft :
  • Acute lung injury, Adaptive, Adaptive immunity, Allele, Allele combinations, Allelic diversity, Animal models, Animals, Antiviral, Antiviral defense, Assay, Baric, Biol, Biological correlates, Biological data, Biological knowledge, Biological parameters, Biology, Brin deposition, Bug, Calu3 cells, Chapel hill, Clinical disease, Collaborative, Comparative analysis, Complex interactions, Computational modeling, Context likelihood, Coronavirus, Critical role, Curr opin microbiol, Cytokine responses, Data analysis, Data generation, Data sources, Database, Datasets, Disease outcomes, Disease pathogenesis, Disease progression, Disease severity, Distress syndrome, Dorf6, Dorf6 infection, Dos, Drug targets, Drug treatment, Drug treatments, Effector functions, Emergent viruses, Epigenetic regulation, Experimental conditions, Experimental data, Experimental design, Experimental systems, Expression data, Expression patterns, Functional assays, Functional consequences, Functional genomics, Functional modules, Functional role, Further studies, Future studies, Gene, Gene ontology, Genetic diversity, Genetic variation, Genome, Gralinski, High mortality rate, Host factors, Host response, Host responses, Host-Pathogen Interactions, Human disease, Human disease models, Human diseases, Humans, Immune, Immune response, Immunol, Immunological, Immunological reviews, Immunological reviews menachery baric bugs, Important aspects, Important role, Inbred, Inbred intercrosses, Infection, Infection conditions, Infectious disease, Infectious disease processes, Infectious disease research, Infectious diseases, Initial studies, Innate immunity, Interferon, Interferon responses, Isgs, Iterative, Iterative cycle, John wiley sons, Josset, Katze, Knockdown studies, Laboratory mouse, Lethal disease, Lethal infection, Mamm genome, Mathematical modeling, Mathematical models, Mechanistic insights, Menachery, Menachery baric bugs, Modeling, Modeling approach, Modeling approaches, Module, Module mapping, Mouse model, Mutant, Mutant viruses, National institutes, Ndings, Novel insights, Novel targets, Novel techniques, Numerous components, Oligogenetic traits, Orf6, Orf6 function, Other areas, Other measurements, Other systems biology groups, Outbred populations, Overall lethality, Pathogen, Pathogenesis, Pathogenic, Pathogenic outcomes, Pathway, Plos pathog, Possible targets, Predictive modeling, Proc natl acad, Proteomics, Proteomics analysis, Reading frame, Receptor, Reductionist, Reductionist approaches, Reductionist science, Reductionistbased approaches, Relatedness method, Replication, Respiratory function, Respiratory pathogens, Respiratory syndrome coronavirus, Respiratory virus infection, Robust, Sarscov, Serpine1, Similar approach, Single nucleotide polymorphisms, Stark differences, Statistical rigor, Subsequent experiments, Syndrome, Syst biol, System biology, Systems approach, Systems biology, Systems biology approach, Systems biology approaches, Systems biology data, Systems biology model, Systems biology paradigm, Systems vaccinology, Systems virology, Target generation, Target genes, Tenet, Therapeutic development, Therapeutic options, Therapeutics, Time course, Time point, Time points, Traditional analysis, Traditional approaches, Transcriptional, Translational Medical Research, Untranslated region, Urokinase, Urokinase pathway, Vaccine, Validation, Validation methods, Validation purposes, Validation studies, Vast datasets, Vast majority, Viral, Viral components, Viral disease, Viral infection, Viral life cycle, Viral mutants, Viral pathogenesis, Viral pathogenesis research, Viral pathogens, Viral proteins, Viral replication, Viral replication kinetics, Virol, Virology, Virulent viruses, Virus, Virus Physiological Phenomena, Virus infection, Vivo, Vivo infection, Vivo studies, Weight loss, Weighted gene network analysis, West nile virus, Wide array, Wiley.

Abstract

• https://api.istex.fr/ark:/67375/WNG-H119DHW4-5/fulltext.pdf

Affiliations:

• États-Unis
• Caroline du Nord
• Chapel Hill (Caroline du Nord)
• Université de Caroline du Nord à Chapel Hill

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